J Biomed Mater Res Part A: 103A: 1357–1365, 2015. Unique mechanism of action Attract, Attach, Activate bone formation Available in Putty and Strip preparations to. Nevertheless, future clinical researches should focus on prospective, randomized, controlled trials in order to fully elucidate whether ABM/P-15 could be a feasible candidate for bone substitute material in orthopedic practices. OSTEOAMP Granules OSTEOAMP Putty Published literature supports the use of OSTEOAMP in both cervical and lumbar spine fusion procedures, and published evidence. ![]() It is suggested that ABM/P-15 might be a good alternative biomaterial for bone implant fixation in this well-validated critical-size defect gap model in sheep. This study revealed that ABM/P-15 had significantly bone formation in concentric gap, and its enhancements on bone formation and implant fixation were at least as good as allograft. Adding HA/βTCP-PDLLA to ABM/P-15 did not significantly change these parameters. The ABM/P-15 group had similar shear mechanical properties on implant fixation as the allograft group. This is the result of the IVANOS study evaluating i-FACTOR peptide enhanced bone graft in lumbar posterolateral spinal surgery. Handling procedure for i-FACTOR Putty: When mixing Putty with autograft. The use of i-FACTOR peptide enhanced bone graft (Cerapedics) resulted in a 50 fusion rate, compared to a 20 fusion rate using allograft in patients with non-instrumented surgery. Bone formation and bone ingrowth to porous titanium implant were not significantly different among the four groups. i-FACTOR Bone Graft comes in a Putty or as a FLEX with purified silk fibers. Tissue volume fraction and thickness were significantly greater in the ABM/P-15 group than in the allograft group. Interestingly, the microarchitecture of the ABM/P-15 group was significantly different from the control group. Grafton Putty consists of demineralized bone fibers and can be mixed with either allograft or autograft bone. a high fusion rate (88.97 for i-Factor and 85.82 for autograft. Significant bone formation and implant fixation could be observed in all four groups. I-FactorTM peptide enhanced bone graft putty must be used inside an mulation used and. ![]() After nine weeks, bone-implant blocks were harvested and sectioned for micro-CT scanning, push-out test, and histomorphometry. Titanium implants with 2-mm concentric gaps were inserted and the gaps were filled with one of the four materials: allograft a synthetic 15-amino acid cell-binding peptide coated hydroxyapatite (ABM/P-15) hydroxyapatite + βtricalciumphosphate+ Poly-Lactic-Acid (HA/βTCP-PDLLA) or ABM/P-15+HA/βTCP-PDLLA. Cylindrical critical size defects were created at the distal femoral condyles bilaterally of eight female adult sheep.
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